1) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Kazutoshi Takahashi, Shinya Yamanaka. Cell. 2006 Aug
25;126(4):663-76.特定因子によるマウス胚性細胞および成体線維芽細胞からの多能性幹細胞の誘導
2) Induction of pluripotent stem cells from adult human fibroblasts by defined factors.
Kazutoshi Takahashi, Koji Tanabe, Shinya Yamanaka.Cell. 2007 Nov 30;131(5):861-72.
特定因子による成人ヒト線維芽細胞からの多能性幹細胞の誘導
3) Rehabilitative Training Enhances Therapeutic Effect of Human-iPSC-Derived Neural Stem/Progenitor Cells Transplantation in Chronic Spinal Cord Injury.
T Shibata, S Tashiro,S Shibata. tem Cells Transl Med. 2023 Mar 3;12(2):83-96.
リハビリテーション訓練は慢性脊髄損傷におけるヒトiPSC由来神経幹細胞/前駆細胞移植の治療効果を高める
4) First-in-human clinical trial of transplantation of iPSC-derived NS/PCs in subacute complete spinal cord injury: Study protocol. K Sugai, M Sumida, T Shofuda. Regenera-tive Therapy V 18, 2021, 321-33.
亜急性完全脊髄損傷患者におけるiPSC由来NS/PC移植のヒト初臨床試験：研究プロトコル
5) Treatment of spinal cord injury by transplantation of human neuroepithelial-like stem cells derived from iPS cell. K Nakashima, Y Fujimoto. Stem cells.2012;30:1163–73.
iPS細胞由来ヒト神経上皮様幹細胞の移植による脊髄損傷の治療
6) Phase I/II trial of iPS-cell-derived dopaminergic cells for Parkinson’s disease.
N Sawamoto, D Doi, E Nakanishi. Nature.641, 971–977 (2025).
パーキンソン病に対する iPS細胞由来ドパミン神経細胞の第 I/II 相臨床試験
7) iPS cell-based therapy for Parkinson's disease: A Kyoto trial. J Takahashi.
パーキンソン病に対するiPS細胞を用いた治療法：京都大学の試験
9) Allogeneic transplantation of iPS cell-derived cardiomyocytes regenerates primate hearts.
Y Shiba, T Gomibuchi, T Seto. Nature. 2016 Oct 20;538(7625):388-391.
iPS細胞由来心筋細胞の同種移植による霊長類の心臓再生法
10) Autologous Induced Stem-Cell-Derived Retinal Cells for Macular Degeneration.
M Mandai, A Watanabe, Y Kurimoto. 黄斑変性に対する自己誘導幹細胞由来網膜細胞
11) Successful Transplantation of Retinal Pigment Epithelial Cells from MHC Homozygote iPSCs in MHC-Matched Models. S Sugita 1, Y Iwasaki, K Makabe. Stme cell reports.
Volume 7, 4, 11 2016, 635-648.
MHC適合モデルにおける、MHCホモ接合体 iPS細胞由来網膜色素上皮細胞の移植成功
12) Clinical translation of human iPSC technologies: advances, safety concerns, and future directions. Front. Cell Dev. Biol., 22 September 202. S Dhaiban. S Chandran.
ヒトiPSC技術の臨床応用：進歩、安全性の懸念、そして将来の方向性
自己脂肪由来幹細胞論文
1) Stem Cell Therapy for Degenerative Disc Disease. D Drazin, J Rosner, P Avalos.
Adv Orthop. 2012 Apr 24;2012:961052. 変性椎間板疾患に対する幹細胞治療
2) Stem cell therapy for degenerative disc disease: Bridging the gap between preclinical promise and clinical potential.
M Munda, T Velnar. Biomol Biomed. 2024 1;24(2):210–218.
変性椎間板疾患に対する幹細胞治療：前臨床研究成果と臨床応用可能性との橋渡し
3) Adipose-derived stem cell therapy for spinal cord injuries: Advances, challenges, and future directions. Y Shimizu, E Ntegea, E Takahara. Regenerative Therapy 26 (2024) 508-519.
脊髄損傷に対する脂肪由来幹細胞治療：進展、課題、今後の展望
4) Adipose-derived stem cells improve the viability of nucleus pulposus cells in dege-nerated intervertebral discs. K Song, T Gu. Mol Med Rep. 2015;12(3):4664-68.
脂肪由来幹細胞は変性椎間板の髄核細胞の生存率を改善する
5) Pain Relief After Allogenic Stem Cell Disc Therapy. Kai-Uwe, A Dowling, J Vera
同種幹細胞による椎間板治療後の疼痛軽減.
6) Potential for Stem Cells Therapy in Alzheimer's Disease: Do Neurotrophic Factors Play Critical Role?. P Bali, D Lahiri, A Banik. Curr Alzheimer Res. 2017;14(2):208-220
アルツハイマー病への幹細胞療法の可能性：神経栄養因子は重要な役割を果たすか？
7) The role of adipose-derived stem cells in knee osteoarthritis treatment: insights rom a triple-blind clinical study. S Sajadi, M Amin, G Raissi. Stem Cell Research & The-rapy Volume 16, 242, (2025).
関節症治療における脂肪由来幹細胞の役割：三重盲検臨床試験からの知見
8) Adipose-derived stem cells applied to ankle pathologies: a systematic review A Arceri A Mazzotti, E Artioli. Musculoskelet Surg. 2023 Nov 9;108(1):1–9.
足関節疾患に対する脂肪由来幹細胞の応用：系統的レビュー
9) Intra-articular injection of mesenchymal stem cells for the treatment of osteoarthritis of the knee: a proof-of-concept clinical trial. C Jo, Y Lee, W Shin. Stem Cells. 2014;32(5)
:1254-66. 膝関節症に対する間葉系幹細胞の関節内注射：概念実証的臨床試験
10) A preliminary report on stem cell therapy for neuropathic pain in humans.
E Vickers, E Karsten, J Flood. J Pain Res. 2014 May 8:7:255-63.
ヒトの神経障害性疼痛に対する幹細胞療法に関する予備報告
11) Advances and challenges in cell therapy for neuropathic pain based on mesenchy-mal stem cells. W Zhang, X Wei Pi, D Hu. Front. Cell Dev. Biol., 21 2025 Volume 13.
間葉系幹細胞に基づく神経障害性疼痛に対する細胞治療の進歩と課題
12) Adipose-Derived Stem Cells for Facial Rejuvenation. A Surowiecka , Strużyna. J Pers Med. 2022 Jan 16;12(1):117.
顔面若返りのための脂肪由来幹細胞
幹細胞上清液論文
1) Mesenchymal Stem Cell-Derived Exosomes: Applications in Regenerative Medicine.
Mangesh D Hade, Caitlin N Suire, Zucai Suo. Cells.2021 Aug 1;10(8):1959.
間葉系幹細胞由来エクソソーム：再生医療への応用
2) Extracellular vesicles: Emerging frontiers in wound healingMangesh D Hade, Caitlin N Suire, James Mossell, Zucai Suo. Med Res Rev. 2022 Nov;42(6):2102-2125
細胞外小胞：創傷治癒における新たなフロンティア
3) Therapeutic potential of mesenchymal stem cell-derived exosomes for regenerative medicine applications. Szymon Roszkowski. Clin Exp Med. 2024 Mar 1;24(1):46.
再生医療への応用に向けた間葉系幹細胞由来エクソソームの治療可能性
4) Adipose-Derived Stem Cell Exosomes Facilitate Rotator Cuff Repair by Mediating Tendon-Derived Stem Cells. G Fu, L Lu, Z Pan. Regenerative Medicine Volume 16, 2021.
脂肪由来幹細胞エクソソームは腱由来幹細胞を媒介して腱板損傷の修復を促進する
5) Factors secreted from dental pulp stem cells show multifaceted benefits for treating experimental rheumatoid arthritis.Ishikawa J, Takahashi N, Matsumoto T, Bone. 2016 Feb:83:210-219.
歯髄幹細胞分泌因子による実験的関節リウマチの治療での多面的効果
6) Conditioned Medium from the Stem Cells of Human Exfoliated Deciduous Teeth Ameliorates Experimental Autoimmune Encephalomyelitis.Shimojima C, Takeuchi H, Jin S. J Immunol. 2016 15;196(10):4164-71.
ヒト乳歯幹細胞培養液による実験的自己免疫性脳脊髄炎の改善
7) Dental Mesenchymal Stem Cell Secretome: An Intriguing Approach for Neuropro-tection and Neuroregeneration. Agnese Gugliandolo, Emanuela Mazzon. Int J Mol Sci. 2021 Dec 31;23(1):456.
歯間葉系幹細胞分泌液の神経保護と神経再生への興味深いアプローチ
8) Therapeutic role of mesenchymal stem cell-derived exosomes in respiratory disease. Mehdi JZ, Saeid K, Mohammad V.Stem Cell Res Ther. 2022 May 12;13(1):194.
呼吸器疾患における間葉系幹細胞由来エクソソームの治療的役割
9) Multifaceted Neuro-Regenerative Activities of Human Dental Pulp Stem Cells for Func-tional Recovery after Spinal Cord Injury. A Yamamoto, K Matsubara, M Ueda. Neurosci Res. 2014 Jan: 78: 16-20.
脊髄損傷後の機能回復へのヒト歯髄幹細胞の多面的な神経再生作用
10) Novel cell-free regeneration of bone using stem cell-derived growth factors. W Katagiri , M Osugi, M Ueda. Int J Oral Maxillofac Implants. 2013 Jul-Aug;28(4):1009-16.
幹細胞由来の成長因子を用いた新しい細胞非依存型の骨再生法
11) Dental Pulp Cell Sheets Enhance Facial Nerve Regeneration via Local Neurotrophic Factor Delivery. M Ahmed, D Shi, M Dailey. Tissue Eng Part A. 2021; 27(17-18):1128-39.
歯髄細胞シートは局所への神経栄養因子供給を介して顔面神経の再生を促進する
血小板再生医療論文
1) Effect of Intra-articular Platelet-Rich Plasma vs Placebo Injection on Pain and Medial Tibial Cartilage Volume in Patients With Knee Osteoarthritis.The RESTORE Randomi-zed Clinical Trial. K Bennell, K Paterson, B Metcalf. JAMA V326, No. 20.
変形性膝関節症患者における関節内多血小板血漿注射とプラセボ注射による疼痛および内側脛骨軟骨容積への影響 RESTOREランダム化臨床試験
2) Efficacy and safety of platelet rich plasma injections for the treatment of knee osteo-arthritis: a systematic review and meta analysis of randomized controlled trials.C Wang, B Yao. European Journal of Medical Research (2025) 30:992.
変形性膝関節症の治療における多血小板血漿注射の有効性と安全性：ランダム化比較試験の系統的レビューとメタアナリシス
3) Clinical Efficacy of Platelet-Rich Plasma and Hyaluronic Acid Versus Hyaluronic Acid for Knee Osteoarthritis with MRI Analysis: A Randomized Controlled Trial. M Zhang, K Chew, P Goh. J Clin Med. 2025 May 19;14(10):3553.
MRI解析による膝関節症に対する多血小板血漿とヒアルロン酸の臨床効果とヒアルロン酸単独の臨床効果の比較
4) A systematic review of randomized control trials looking at functional improvement of rotator cuff partial thickness tears following platelet-rich-plasma injection: a compa-rison of glenohumeral joint vs. subacromial bursa vs. intratendinous injection locations. M Dakkak, A Saleemz, D Patel. JSES International 8 (2024) 464e471.
多血小板血漿注入後の肩回旋腱板部分断裂の機能改善を検討したランダム化比較試験の系統的レビュー：肩甲上腕関節、肩峰下滑液包、腱内注射部位の比較
5) Ultrasound-guided injection of platelet rich plasma versus corticosteroid for treat-ment of rotator cuff tendinopathy: Effect on shoulder pain, disability, range of motion and ultrasonographic findings. D Ibrahim, N Gazzar, H Saadan. The Egyptian Rheuma-tologist. V 41,2, 2019, 157-161.
腱板炎の治療における超音波ガイド下多血小板血漿注入とコルチコステロイドの比較：肩の痛み、障害、可動域、超音波画像所見への影響
6) Platelet-rich plasma injections for chronic plantar fasciitis. N Martinelli, A Marinozz, S Carnì. Int Orthop. 2012 19;37(5):839–842.
慢性足底筋膜炎に対する多血小板血漿注射
7) Effects of platelet-rich plasma on lateral epicondylitis of the elbow: prospective randomized controlled trial. E Palacio, R Schiavetti, M Kanematsu. Rev Bras Ortop. V 51, 1, 2016, 90-95.
多血小板血漿の肘外側上顆炎への効果：前向きランダム化比較試験
8) Stem-cell therapy and platelet-rich plasma in regenerative medicines: A review on pros and cons of the technologies. S Reddy, R Reddy, N Babu. J Oral Maxillofac Pathol. 2018 ;22(3):367–374.
再生医療における幹細胞療法と多血小板血漿：技術の長所と短所のレビュー
9) Platelet-Rich Plasma in Facial Rejuvenation: A Systematic Appraisal of the Available Clinical Evidence. H Xiao, D Xu, R Mao. Clinical, Cosmetic and Investigational Dermato-logy 2021:14 1697–1724.
顔面若返りにおける多血小板血漿：利用可能な臨床的エビデンスの体系的評価
